GLP-1 weight-loss clinics in Sioux Falls, South Dakota
48 Sioux Falls clinics ranked by Trust Score — with real prices, LegitScript status, and patient reviews. Median program: $218/mo.
Price-Transparency Comparison
Top 10 of 48 matched| Clinic | Monthly Range | Meds Included | Insurance | Verification |
|---|---|---|---|---|
| SummaUp | From $200/mo | Cash pay | 2 of 5 verified | |
| Encompass Wellness & Aesthetics | — | Cash pay | 2 of 5 verified | |
| Sioux Falls Secret for Weight Loss | — | Cash pay | 1 of 5 verified | |
| The Retreat at Cedar Creek - Sioux Falls Weight Loss, Red Light Body Contouring & Wellness Center | — | Cash pay | 1 of 5 verified | |
| Functional Health Clinic | — | Cash pay | 1 of 5 verified | |
| Profile Plan - Personalized Weight Loss Plans (Virtual Location) | — | Cash pay | 1 of 5 verified | |
| Avera Medical Group McGreevy — 7th Ave | — | Cash pay | 1 of 5 verified | |
| Trillion Health and Hormone Clinic | — | Cash pay | 2 of 5 verified | |
| Avera Pharmacy — McKennan Campus | — | Cash pay | 1 of 5 verified | |
| Avera Pharmacy — Plaza 2 | — | Cash pay | 1 of 5 verified |
Ranked Providers
SummaUp
Updated 124h agoEncompass Wellness & Aesthetics
Updated 121h agoSioux Falls Secret for Weight Loss
Updated 124h agoThe Retreat at Cedar Creek - Sioux Falls Weight Loss, Red Light Body Contouring & Wellness Center
Updated 125h agoProfile Plan - Personalized Weight Loss Plans (Virtual Location)
Updated 125h agoAvera Medical Group McGreevy — 7th Ave
Updated 124h agoTrillion Health and Hormone Clinic
Updated 121h agoAvera Pharmacy — McKennan Campus
Updated 125h agoCareTrends Pharmacy
Updated 125h agoSioux Falls Specialty Hospital
Updated 121h agoPrime IV Hydration & Wellness - Sioux Falls
Updated 124h agoProfile Plan - Personalized Weight Loss Plans (Virtual Location)
Updated 124h agoAnnie Ailts, RD - Dietitian Nutritionist
Updated 125h agoRadiant Health and Hormone Therapy
Updated 124h agoLaVie Ideal Protein Virtual Clinic
Updated 124h agoSanford Weight Management Center
Updated 124h agoLimitless Male Medical Clinic
Updated 124h agoPlastic Surgery Associates of South Dakota Ltd
Updated 121h agoSioux Falls Hypnosis
Updated 124h agoEra Health
Updated 124h agoGameday Men's Health Sioux Falls, SD
Updated 124h agoAccelerate Wellness - Longevity Medicine Clinic
Updated 124h agoPharmacy Specialties & Clinic, Inc.
Updated 121h agoSurgical Institute of South Dakota, PC
Updated 121h agoSouth Dakota Urban Indian Health - Sioux Falls Clinic
Updated 124h agoAvera Specialty Pharmacy — Sioux Falls
Updated 125h agoSanford Surgical Associates
Updated 125h agoAvera McKennan Hospital & University Health Center
Updated 125h agoAvera Comprehensive Weight Management — 41st & Holbrook
Updated 124h agoRise & Renew: A Mounjaro Clinic
Updated 125h agoFrequently Asked Questions
How many GLP-1 weight-loss clinics are in Sioux Falls, South Dakota?
TrimSoMo tracks 48 verified GLP-1 clinics in Sioux Falls. Each is scored 0–100 on the TrimSoMo Trust Score so you can compare verification, price transparency, and reviews.
How much does GLP-1 treatment cost in Sioux Falls?
Across the 48 clinics we track in Sioux Falls, the median GLP-1 program runs about $218/mo. For reference, brand-name Wegovy or Zepbound without insurance is typically $1,000–$1,400/mo, while compounded semaglutide can start around $179/mo.
Do GLP-1 clinics in Sioux Falls accept insurance?
0% of the GLP-1 clinics we list in Sioux Falls accept insurance. Coverage varies by plan — most large employer plans now cover GLP-1 for obesity if BMI ≥ 30 (or ≥ 27 with comorbidities), and prior authorization is usually required. Use the "Accepts insurance" filter above to see them.
Brand-name vs compounded GLP-1 — which is right for me?
Brand-name (Wegovy, Zepbound) is FDA-approved and consistent. Compounded versions are made by 503A/503B pharmacies, often cheaper but less regulated. Availability and legality of compounded GLP-1 are changing under evolving FDA rules (2025–2026) — choose certified clinics and confirm current options directly.
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